The Department of Biochemistry’s seminar series, called the Tea Club, will restart on Tuesday 15th October at 12:00pm in the Jean Thomas Lecture Theatre.
The first talk of the academic year will be given by Haoxi Wu, of the UK Resarch and Innovation's world-class MRC Laboratory of Molecular Biology.
Haoxi Wu (MRC Laboratory of Molecular Biology), who will give a seminar titled 'mechanism for membrane protein insertion and complex assembly'.
Haoxi will be hosted by Marc de la Roche.
Abstract: The human genome encodes approximately 5000 membrane proteins of varied sizes, shapes, and biophysical properties. To function properly, most of these proteins need to be inserted into the membrane in the correct orientation, folded into their three-dimensional structure, and assembled with partner proteins. How these membrane proteins are correctly made is not well understood. Using a biochemical approach to study factors involved in membrane protein biogenesis, I will discuss an emerging and unifying model for membrane protein insertion and the identification and characterization of assembly factors that facilitate complex formation.
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